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CIE 0610 Biology · IGCSE · Topic 9

Transport in animals

CIE 0610 BiologyIGCSEFree revision notes

Contents: 7 sections

Single and double circulation

A double circulation means blood passes through the heart twice for each complete circuit of the body.

Fish have a single circulation: blood passes through the heart once per circuit, going heart → gills → body → heart.

The advantage of a double circulation is the one to state precisely. Blood loses pressure passing through the narrow capillaries of the lungs. In a double circulation it returns to the heart and is re-pressurised before going to the body, so it can be delivered quickly and at high pressure. In a single circulation the blood reaching the body has already lost most of its pressure, so delivery is slower. Mammals need the faster delivery because they maintain a constant body temperature and have a high metabolic rate.

The heart

Four chambers: two atria on top, two ventricles below.

Diagram walkthrough · 2 minTracing one drop of blood through all four chambersAmoeba SistersFollows deoxygenated blood from a toe all the way round, naming each chamber, valve and vessel in order and saying which chamber contracts at each step. The full sequence is then repeated at speed as a self-test, which is how this gets memorised.

The right side handles deoxygenated blood, the left side oxygenated. Remember that on a diagram the heart is drawn as if facing you, so the right side appears on the left of the page.

The route through it:

vena cava → right atrium → right ventricle → pulmonary artery → lungs → pulmonary vein → left atrium → left ventricle → aorta → body

The pulmonary artery is the only artery carrying deoxygenated blood, and the pulmonary vein the only vein carrying oxygenated blood. That pair is asked about constantly, because it breaks the usual rule.

Why the left ventricle wall is thicker. It pumps blood to the whole body, which needs a much higher pressure, so it needs more muscle. The right ventricle pumps only to the lungs, which are close by, and too high a pressure would damage the delicate capillaries there.

Valves keep blood flowing one way. The atrioventricular valves stop backflow from ventricles into atria; the semilunar valves stop backflow from the arteries into the ventricles. A valve opens when pressure behind it is higher and closes when pressure in front is higher.

Exercise and heart rate

During activity, muscles respire faster, so they need more oxygen and glucose and produce more carbon dioxide. Heart rate and stroke volume rise, so more blood is delivered each minute, and the carbon dioxide is carried away faster.

Heart rate stays high for a while afterwards, repaying the oxygen debt built up by anaerobic respiration and clearing the lactic acid.

Coronary heart disease

The coronary arteries supply the heart muscle itself with oxygen and glucose. If fatty material builds up in their walls, the artery narrows and the blood flow falls. If the muscle is starved of oxygen it cannot respire, and a blockage causes a heart attack.

Risk factors: a diet high in saturated fat, smoking, lack of exercise, stress, obesity, age and genetic factors.

Prevention follows the same list: less saturated fat, no smoking, regular exercise, healthy weight. Treatments include stents to widen the artery and bypass surgery.

Blood vessels

ArteryVeinCapillary
Directionaway from hearttowards heartbetween the two
Wallthick, muscle and elastic tissuethinone cell thick
Lumennarrowwidevery narrow
Valvesnoneyesnone
Pressurehighlowfalling

Each feature answers a need. An artery's thick elastic wall withstands and smooths the high pressure from each heartbeat. A vein's wide lumen reduces resistance where pressure is low, and valves stop backflow because there is little pressure to keep blood moving; blood in veins is helped along by the contraction of nearby skeletal muscles.

A capillary is one cell thick so the diffusion distance is short, and capillaries form dense networks so no cell is far from a supply.

Blood

Four components, each with a clear function.

A common question shows a cell under a microscope and asks for its function. A cell with no nucleus and a pale centre is a red blood cell, carrying oxygen; a large cell with a lobed nucleus is a phagocyte, engulfing pathogens.

Check you have it

Question 1

Which row shows the features of a blood vessel that transports blood at low pressure? Each answer gives, in order: size of lumen; thickness of wall; valves.

Table from the Cambridge Biology 0610 Paper 2 October/November 2024 paper, variant 1, question 19.

Question 2

What are methods for monitoring the activity of the heart? Each answer gives, in order: ECG; measuring pulse rate; listening to sounds of valves closing.

Diagram from the Cambridge Biology 0610 Paper 1 May/June 2024 paper, variant 1, question 22.

Question 3

The flow diagram shows stages in blood clotting. components of blood loss blood involved in component Y and clotting circulate forms a mesh pathogen the body entry stops
What is component X?

Diagram from the Cambridge Biology 0610 Paper 2 May/June 2022 paper, variant 2, question 18.
What the syllabus asks for on this topicSyllabus points

Syllabus points

  • Describe the circulatory system as a system of blood vessels with a pump and valves.
  • Explain the advantages of a double circulation.
  • Describe the structure and function of the heart and the effect of physical activity on heart rate.
  • Describe coronary heart disease, its risk factors and its prevention.
  • Describe the structure and functions of arteries, veins and capillaries.
  • List the components of blood and state their functions.

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